Jannatul Aklima, MS
Mitochondrial biology (Biotechnology & life science)
Tokyo University of Agriculture & Technology, Tokyo-Japan
Ms. Jannatul Aklima completed her B.Sc. and MS degrees from the Department of Biochemistry and Molecular Biology, University of Chittagong, Bangladesh. She has joined at EuGEF from 2016 and was involved in the project targeted to identify novel diagnostic, prognostic and therapeutic approaches for cancer patients. Now, she is pursuing her PhD on Mitochondrial biology, Tokyo University of Agriculture & Technology, to understand significance of mitochondrial transient depolarization and its interrelationship with matrix pH and ROS generation, by using isolated single mitochondria. She wants to contribute the society through her research findings in biological sciences. She enjoys her time with family and watching movies.
Chemotherapeutic resistance of head and neck squamous cell carcinoma is mediated by EpCAM induction driven by IL-6/p62 associated Nrf2-antioxidant pathway activation. Noman ASM, Parag RR, Rashid MI, Islam S, Rahman MZ, Chowdhury AA, Sultana A, Jerin C, Siddiqua A, Rahman L, Nayeem J, Akther S, Baidya S, Shil RK, Rahman M, Shirin A, Mahmud R, Hossain SMI, Sumi SA, Chowdhury A, Basher SB, Hasan A, Bithy S, Aklima J, Chowdhury N, Hasan MN, Banu T, Chowdhury S, Hossain MM, Yeger H, Farhat WA, Islam SS. Cell Death Dis. 2020 Aug 20;11(8):663. doi: 10.1038/s41419-020-02907-x. PMID: 32814771.
Widespread expression of Sonic hedgehog (Shh) and Nrf2 in patients treated with cisplatin predicts outcome in resected tumors and are potential therapeutic targets for HPV-negative head and neck cancer. Noman ASM, Parag RR, Rashid MI, Rahman MZ, Chowdhury AA, Sultana A, Jerin C, Siddiqua A, Rahman L, Shirin A, Nayeem J, Mahmud R, Akther S, Shil RK, Hossain I, Alam S, Chowdhury A, Basher SB, Hasan A, Bithy S, Aklima J, Rahman M, Chowdhury N, Banu T, Karakas B, Yeger H, Farhat WA, Islam SS. Ther Adv Med Oncol. 2020 Mar 13; 12:1758835920911229. doi: 10.1177/1758835920911229. eCollection 2020. PMID: 32206093.
Leea Leea macrophylla Roxb. leaf extract potentially helps normalize islet of β-cells damaged in STZ-induced albino rats. Rahman MA, Chowdhury JMKH, Aklima J, Azadi MA. Food Sci Nutr. 2018 Mar 30;6(4):943-952. doi: 10.1002/fsn3.625. eCollection 2018 Jun. PMID: 29983957.Evaluation of hypoglycemic status and causative factors in neonatal sepsis. Md Zahirul Islam, Jannatul Aklima, Farhana Yesmin, Mohammad Sayedul Islam, Kanchan Chakma, Mohammad Alauddin, Robiul Hasan Bhuiyan. International Journal of Contemporary Pediatrics 4 (6), 1927 Medip Academy, 2017.
Antioxidative and neuroprotective effects of Leea macrophylla methanol root extracts on diazepam-induced memory impairment in amnesic Wistar albino rat. S Ferdousy, MA Rahman, MM Al-Amin, J Aklima, JMKH Chowdhury. Clinical Phytoscience 2 (1), 1-11, 2017.
Antioxidative role of Hatikana (Leea macrophylla Roxb.) partially improves the hepatic damage induced by CCl4 in Wistar albino rats. S Akhter, MD Rahman, J Aklima, MD Hasan, JM Hasan Chowdhury. Biomed Res Int. 2015; 2015:356729. doi: 10.1155/2015/356729. Epub 2015 Jun 14. PMID: 26221590
Antithrombotic effects of five organic extracts of Bangladeshi plants in vitro and mechanisms in in silico models. Mahmud S, Akhter S, Rahman MA, Aklima J, Akhter S, Merry SR, Jubair SM, Dash R, Emran TB. Evid Based Complement Alternat Med. 2015:782742. doi: 10.1155/2015/782742. Epub 2015 May 17. PMID: 26075001