Ayesha Siddiqua, MS
Ayesha Siddiqua has completed her BSc and MS degree from the Department of Biochemistry and Molecular Biology, University of Chittagong, Bangladesh, and started her research journey in March 2015 at Laboratory of Eukaryotic Gene Expression and Function, BMB, CU. At EuGEF she is involved in number of projects. Primarily, she focuses on the frequency determination of breast lesions by FNAC under the supervision of Dr. ASM Noman to identify frequency of both benign and malignant lesions in Chittagong region along with the efficiency & efficacy of FNAC as primary diagnostic approach. Now, she is working at EuGEF Lab to find novel mutation of regulatory factor in cancer pathogenesis under the supervision of Drs. ASM Noman, MM Hossain, and S. Chowdhury. Besides, she is also involve in breast cancer project to explore the role of epigenetic changes in the down-regulation of miRNAs in breast cancer.
Outside the lab, she is interested in reading, traveling, watching movies etc. She enjoys her leisure time with family and friends.
Serum sonic hedgehog (SHH) and interleukin-(IL-6) as dual prognostic biomarkers in progressive metastatic breast cancer. Noman AS, Uddin M, Chowdhury AA, Nayeem MJ, Raihan Z, Rashid MI, Azad AK, Rahman ML, Barua D, Sultana A, Shirin A, Ferdous J, Parag RR, Rahman SM, Mahmud MR, Jerin CS, Jahan N, Siddiqua A. Scientific Reports. 2017 May 11;7(1):1796; doi: 10.1038/s41598-017-01268-4; PMID: 28496132
Widespread expression of Sonic hedgehog (Shh) and Nrf2 in patients treated with cisplatin predicts outcome in resected tumors and are potential therapeutic targets for HPV-negative head and neck cancer. Noman AS, Parag RR, Rashid MI, Rahman MZ, Chowdhury AA, Sultana A, Jerin C, Siddiqua A, Rahman L, Shirin A, Nayeem J, et al., Therapeutic Advances in Medical Oncology. 2020 Mar 13;12:1758835920911229; doi: 10.1177/1758835920911229; PMID: 32206093
Chemotherapeutic resistance of head and neck squamous cell carcinoma is mediated by EpCAM induction driven by IL-6/p62 associated Nrf2-antioxidant pathway activation. Noman ASM, Parag RR, Rashid MI, Islam S, Rahman MZ, Chowdhury AA, Sultana A, Jerin C, Siddiqua A, Rahman L, et al., Cell Death & Disease. 2020 Aug 20;11(8):663; doi: 10.1038/s41419-020-02907-x; PMID: 3281477