Sharmin Alam Sumi, MS

 

Member,

EuGEF Research Group

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Ms. Sharmin Alam Sumi received her BSc and MS degree from the Department of Biochemistry and Molecular Biology, University of Chittagong, Bangladesh and started her research career in January 2016 at Laboratory of Eukaryotic Gene Expression and Function, BMB, CU. At EuGEF she was involved in number of projects. Earlier, she focused on the role of sonic hedgehog level in blood serum of breast cancer patients under the supervision of Dr. ASM Noman to identify novel diagnostic, prognostic and therapeutic approaches for cancer patients. Beside she was actively involved in epidemiological field investigations on screening cancer and pediatric congenital disease patients with demographic data based on ethnic region in Bangladesh.

Now, she is working at CRICS under the supervision of Prof. Dr. Tahmina Banu and assigned to investigate the risk factors of birth defect and pediatric surgical condition in Bangladesh.

Outside the lab, she likes to read story books and scientific articles. She spends her leisure time with family.

 

Selected Publications:

 

• Widespread expression of Sonic hedgehog (Shh) and Nrf2 in patients treated with cisplatin predicts outcome in resected tumors and are potential therapeutic targets for HPV-negative head and neck cancer. Noman AS, Parag RR, Rashid MI, Rahman MZ, Chowdhury AA, Sultana A, Jerin C, Siddiqua A, Rahman L, Shirin A, Nayeem J, Alam S, et al.,Therapeutic Advances in Medical Oncology. 2020 Mar 13;12:1758835920911229;doi: 10.1177/1758835920911229; PMID: 32206093

 

• Chemotherapeutic resistance of head and neck squamous cell carcinoma is mediated by EpCAM induction driven by IL-6/p62 associated Nrf2-antioxidant pathway activation.Noman ASM, Parag RR, Rashid MI, Islam S, Rahman MZ, Chowdhury AA, Sultana A, Jerin C, Siddiqua A, Rahman L, Sharmin A. Sumi, et al., Cell Death & Disease. 2020 Aug 20;11(8):663;doi: 10.1038/s41419-020-02907-x;PMID: 3281477